abstract：OBJECTIVE:The neurotransmitter serotonin (5-HT) has been linked to the underlying biological processes related to aggressive behaviour. However, only a few studies on this subject involving young people have been published so far. METHOD:We aimed to investigate the effects of acute tryptophan depletion (ATD) on reacti...

journal_title：Acta psychiatrica Scandinavica

authors： Kötting WF,Bubenzer S,Helmbold K,Eisert A,Gaber TJ,Zepf FD

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To explore the possibility that autism, catatonia and psychoses in children are different manifestations of a single underlying form of brain pathology - a kind of 'Iron Triangle' of symptomatology - rather than three separate illnesses. METHOD:Systematic evaluation of historical case literature on autism to...

journal_title：Acta psychiatrica Scandinavica

authors： Shorter E,Wachtel LE

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To assess the economic impact of the duration of antidepressant drug treatment in a real-life setting. METHOD:A historical fixed cohort study included 27 917 patients aged 18 and over with a new antidepressant treatment registered in the national insurance database. The economic impact concerned healthcare e...

journal_title：Acta psychiatrica Scandinavica

authors： Tournier M,Crott R,Gaudron Y,Verdoux H

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To combine the results of earlier comparison studies of in-patient aggression to quantitatively assess the strength of the association between patient factors and i) aggressive behaviour,ii) repetitive aggressive behaviour. METHOD:A systematic review and meta-analysis of empirical articles and reports of com...

journal_title：Acta psychiatrica Scandinavica

authors： Dack C,Ross J,Papadopoulos C,Stewart D,Bowers L

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To investigate the predictive value of the Strauss and Carpenter Prognostic Scale (SCPS) for transition to a first psychotic episode in subjects clinically at high risk (CHR) of psychosis. METHOD:Two hundred and forty-four CHR subjects participating in the European Prediction of Psychosis Study were assessed...

journal_title：Acta psychiatrica Scandinavica

authors： Nieman DH,Velthorst E,Becker HE,de Haan L,Dingemans PM,Linszen DH,Birchwood M,Patterson P,Salokangas RK,Heinimaa M,Heinz A,Juckel G,von Reventlow HG,Morrison A,Schultze-Lutter F,Klosterkötter J,Ruhrmann S,EPOS group.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To measure how primary care physicians (PCPs) and psychiatrists treat mild depression. METHOD:We surveyed a national sample of US PCPs and psychiatrists using a vignette of a 52-year-old man with depressive symptoms not meeting Major Depressive Episode criteria. Physicians were asked how likely they were to ...

journal_title：Acta psychiatrica Scandinavica

authors： Lawrence RE,Rasinski KA,Yoon JD,Meador KG,Koenig HG,Curlin FA

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To identify trajectories of depressive symptoms in older community residents. METHOD:Depressive symptomatology, based on a modified Center for Epidemiological Studies-Depression scale, was obtained at years 0, 3, 6, and 10, in the Duke Established Populations for Epidemiologic Studies of the Elderly (n = 416...

journal_title：Acta psychiatrica Scandinavica

authors： Kuchibhatla MN,Fillenbaum GG,Hybels CF,Blazer DG

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Deficits in social cognition have been reported in euthymic subjects with bipolar disorder (BD). However, some studies have failed to find differences favoring controls. As most investigations have been conducted with small samples, they have not had sufficient power to detect statistically significant differ...

journal_title：Acta psychiatrica Scandinavica

authors： Samamé C,Martino DJ,Strejilevich SA

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:The aim of this 1-year follow-up study was to compare functional outcome as well as clinical differences between patients with first- and multiple-episode bipolar disorder. METHOD:Bipolar disorder patients with first (n = 60) and multiple episodes (n = 59) were recruited from two hospitals in Spain. The Func...

journal_title：Acta psychiatrica Scandinavica

authors： Rosa AR,González-Ortega I,González-Pinto A,Echeburúa E,Comes M,Martínez-Àran A,Ugarte A,Fernández M,Vieta E

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVE:There have been increasing pressures to adopt or incorporate dimensional representations in various sections of DSM-5 including the psychotic disorders section. Thus far, findings offered as evidence of a continuous distribution of psychosis are limited given their exclusive focus on the manifest rather than ...

journal_title：Acta psychiatrica Scandinavica

authors： Ahmed AO,Buckley PF,Mabe PA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Prolonged duration is commonly used as an indicator that bereavement-related depression (BRD) is pathological. DSM-IV replaced the traditional 1-year pathology cut-point by a 2-month cut-point. Yet, little evidence exists regarding the validity of these cut-points in indicating increased BRD severity. This st...

journal_title：Acta psychiatrica Scandinavica

authors： Wakefield JC,Schmitz MF,Baer JC

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the like...

journal_title：Acta psychiatrica Scandinavica

authors： Zanarini MC,Hörz S,Frankenburg FR,Weingeroff J,Reich DB,Fitzmaurice G

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:Despite comparable antipsychotic exposure, some patients experience involuntary movements yet others do not. Negative symptoms have been associated with tardive dyskinesia (TD), but it is not certain whether this is an association with primary negative symptoms or the effects of medications. The aim of the pr...

journal_title：Acta psychiatrica Scandinavica

authors： Telfer S,Shivashankar S,Krishnadas R,McCreadie RG,Kirkpatrick B

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The endocannabinoid (EC) system is widely distributed throughout the brain and modulates many functions. It is involved in mood and related disorders, and its activity may be modified by exogenous cannabinoids. This article examines the therapeutic potential of cannabinoids in psychiatric disorders. METHOD:A...

journal_title：Acta psychiatrica Scandinavica

authors： Ashton CH,Moore PB

更新日期：2011-10-01 00:00:00

abstract：UNLABELLED:Van den Eynde F, Guillaume S, Broadbent H, Stahl D, Campbell IC, Schmidt U, Tchanturia K. Neurocognition in bulimic eating disorders: a systematic review. OBJECTIVE:  The aim of this study was to review the literature on neurocognition comparing people with a bulimic eating disorder in the acute phase of th...

journal_title：Acta psychiatrica Scandinavica

authors： Van den Eynde F,Guillaume S,Broadbent H,Stahl D,Campbell IC,Schmidt U,Tchanturia K

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:Prefrontal cortical dysfunction has been implicated in the pathophysiology of schizophrenia but it is unclear to what extent these are related to changes in symptomatology as well as task demand. METHOD:We examined the neural correlates of symptom change and task demand during a longitudinal functional magne...

journal_title：Acta psychiatrica Scandinavica

authors： Smee C,Krabbendam L,O'Daly O,Prins AM,Nalesnik N,Morley L,Samson G,Shergill S

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:The primary aim of the study was to compare the effectiveness of group and individual cognitive behaviour therapy (CBT) for obsessive compulsive disorder (OCD). METHOD:One hundred and ten out-patients with OCD were randomly assigned to 15 sessions of either group CBT or individual CBT. Outcome measures were ...

journal_title：Acta psychiatrica Scandinavica

authors： Jónsson H,Hougaard E,Bennedsen BE

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:To assess the methodological value of studies that signaled one or more selective serotonin reuptake inhibitors (SSRIs) as teratogenic agents. METHOD:Medical literature, published in English (1980-November 2010), was searched using MEDLINE/PubMed, TOXNET, EMBASE, and The Cochrane Library to identify all arti...

journal_title：Acta psychiatrica Scandinavica

authors： Gentile S

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:To record risk factors for breast cancer in women with schizophrenia and recommend preventive actions. METHOD:A PubMed literature search (from 2005 to 2010) was conducted, using the search terms 'schizophrenia', 'antipsychotics', 'breast cancer' and 'risk factors'. RESULTS:Several risk factors of relevance ...

journal_title：Acta psychiatrica Scandinavica

authors： Seeman MV

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Autism appears to have a strong genetic component. The product of the NADH-ubiquinone oxidoreductase 1 alpha subcomplex 5 (NDUFA5) gene is included in the mitochondrial electron transport chain. METHOD:We performed a case-control study of 235 patients with autism and 214 controls and examined three single-nu...

journal_title：Acta psychiatrica Scandinavica

authors： Marui T,Funatogawa I,Koishi S,Yamamoto K,Matsumoto H,Hashimoto O,Jinde S,Nishida H,Sugiyama T,Kasai K,Watanabe K,Kano Y,Kato N

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Renewed insight into dose-related effects of sertindole and haloperidol was sought by re-analysing published data for antipsychotic effect, extrapyramidal effect, and patient wellbeing - i.e., the important pharmacopsychometric triangle domains. METHOD:Selected Positive and Negative Syndrome Scale (PANSS) su...

journal_title：Acta psychiatrica Scandinavica

authors： Bech P,Tanghøj P,Andreasson K,Overø KF

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:Antidepressant medications are efficacious overall; however, some individuals experience worsening mood symptoms and increased suicidal ideation (SI) during treatment. We examined the quantitative electroencephalographic (QEEG) cordance biomarker of brain function biomarker in relation to treatment-emergent s...

journal_title：Acta psychiatrica Scandinavica

authors： Hunter AM,Leuchter AF,Cook IA,Abrams M

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Patients who engage in recurrent deliberate self-harm (DSH) behaviours have increased morbidity and mortality and use emergency services more than others. Unrecognized iatrogenic injury may play a role. Specifically, we call attention to the potential danger of cumulative radiation exposure. METHOD:Case pres...

journal_title：Acta psychiatrica Scandinavica

authors： Norelli LJ,Coates AD,Kovasznay BM

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To examine secular trends in the prevalence of Alzheimer's disease (AD) and vascular dementia (VD) in a general Japanese population. METHOD:Four cross-sectional examinations were conducted among residents of a Japanese community aged >or=65 in 1985, 1992, 1998 and 2005. RESULTS:The age- and sex-adjusted pre...

journal_title：Acta psychiatrica Scandinavica

authors： Sekita A,Ninomiya T,Tanizaki Y,Doi Y,Hata J,Yonemoto K,Arima H,Sasaki K,Iida M,Iwaki T,Kanba S,Kiyohara Y

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To evaluate cognitive behaviour therapy for psychosis (CBTp) delivered by non-expert therapists, using CBT relevant measures. METHOD:Participants (N = 74) were randomised into immediate therapy or waiting list control groups. The therapy group was offered 6 months of therapy and followed up 3 months later. T...

journal_title：Acta psychiatrica Scandinavica

authors： Peters E,Landau S,McCrone P,Cooke M,Fisher P,Steel C,Evans R,Carswell K,Dawson K,Williams S,Howard A,Kuipers E

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To examine factors increasing the risk for onset and persistence of subthreshold mania and depression. METHOD:In a prospective cohort community study, the association between risk factors [a family history of mood disorders, trauma, substance use, attention-deficit/hyperactivity disorder (ADHD) and temperame...

journal_title：Acta psychiatrica Scandinavica

authors： Tijssen MJ,Van Os J,Wittchen HU,Lieb R,Beesdo K,Wichers M

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Sanfilippo B is a rare autosomal recessive mucopolysaccharidosis (MPS IIIB) caused by a deficiency of N-acetyl-alpha-D-glucosaminidase (NAGLU). METHOD:A mild mentally retarded elderly female patient is described with a slowly progressive dementia who had given birth to a daughter who developed normally. RES...

journal_title：Acta psychiatrica Scandinavica

authors： Verhoeven WM,Csepán R,Marcelis CL,Lefeber DJ,Egger JI,Tuinier S

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To describe the impact of tobacco, alcohol and cannabis on metabolic profile and cardiovascular risk in bipolar patients. METHOD:Naturalistic, cross-sectional, multicenter Spanish study. Current use of tobacco, alcohol and cannabis was determined based on patient self-reports. Metabolic syndrome was defined ...

journal_title：Acta psychiatrica Scandinavica

authors： Garcia-Portilla MP,Saiz PA,Benabarre A,Florez G,Bascaran MT,Díaz EM,Bousoño M,Bobes J

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:We examine the safety and efficacy of venlafaxine monotherapy in bipolar type II (BP II) patients with major depressive episode (MDE) who were unresponsive to prior lithium monotherapy. We hypothesized that venlafaxine would be superior to lithium with a low hypomanic conversion rate. METHOD:Seventeen patien...

journal_title：Acta psychiatrica Scandinavica

authors： Amsterdam JD,Wang G,Shults J

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:The amygdala plays a major role in processing emotional stimuli. Fourteen studies using structural magnetic resonance imaging (MRI) have examined the amygdala volume in paediatric and adult patients with bipolar disorder (BD) compared with healthy controls (HC) and reported inconsistent findings. Lithium has ...

journal_title：Acta psychiatrica Scandinavica

authors： Usher J,Menzel P,Schneider-Axmann T,Kemmer C,Reith W,Falkai P,Gruber O,Scherk H

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:The main objective of this study was to assess the prevalence of common mental disorders in the Moroccan general population. METHOD:On a systematic representative randomized sample, the Moroccan Arabic version of the Mini International Neuropsychiatric Interview (MINI) was used to assess the prevalence of mo...

journal_title：Acta psychiatrica Scandinavica

authors： Kadri N,Agoub M,Assouab F,Tazi MA,Didouh A,Stewart R,Paes M,Toufiq J,Moussaoui D

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:The study aimed to increase the knowledge about the detailed course differences between different forms of bipolar disorder. METHOD:Using the prospective life-chart-clinician version, we compared the fine-grain analysis of mood swings and treatment modalities of 18 bipolar II with 31 bipolar I patients. RES...

journal_title：Acta psychiatrica Scandinavica

authors： Born C,Seitz NN,Grunze H,Vieta E,Dittmann S,Seemüller F,Amann B

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:Much of the knowledge we now take for granted regarding major mental disorders such as schizophrenia, suicide and other disorders, would not exist without the use of population based registers. The use of population based registers in psychiatric epidemiology have enabled analyses of associations that otherwi...

journal_title：Acta psychiatrica Scandinavica

authors： Allebeck P

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To identify possible differences in the mean midsagittal corpus callosum (CC) total and subdivision areas in treatment-resistant schizophrenia and depression (TRS and TRD) patients. METHOD:Areas of the total CC and its five equidistant subregions (from CC1 to CC5) obtained by parallel grid partitioning schem...

journal_title：Acta psychiatrica Scandinavica

authors： Sun J,Maller JJ,Daskalakis ZJ,Furtado CC,Fitzgerald PB

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVE:The aim was to elucidate the relationship between psychotic and behavioural symptoms in the elderly. METHOD:A representative sample of 85 year old subjects living in Gothenburg, Sweden (n = 451) was assessed with neuropsychiatric examinations, key informant interviews and record reviews. RESULTS:Fourteen pe...

journal_title：Acta psychiatrica Scandinavica

authors： Ostling S,Gustafson D,Waern M

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To examine factors contributing to variance in functional outcome in first-episode psychosis (FEP) following 1 year of treatment. METHOD:Naturalistic 1-year follow-up of a FEP cohort (n = 200), from programs in four university centers in Ontario, Canada. Functional recovery was defined by 'Social and Occupat...

journal_title：Acta psychiatrica Scandinavica

authors： Menezes NM,Malla AM,Norman RM,Archie S,Roy P,Zipursky RB

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:There are several complications associated with heroin abuse, some of which are life-threatening. Methadone may aggravate this problem. METHOD:A clinical case description. RESULTS:A 33-year-old man presented with rhabdomyolysis and cerebral ischemic stroke after intravenous heroin. He had used heroin since ...

journal_title：Acta psychiatrica Scandinavica

authors： Hsu WY,Chiu NY,Liao YC

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:There are hardly any randomised-controlled trials of structured family interventions for schizophrenia from India. This study attempted to evaluate the impact of a structured psychoeducational intervention for schizophrenia, compared with standard out-patient treatment, on various patient- and caregiver-relat...

journal_title：Acta psychiatrica Scandinavica

authors： Kulhara P,Chakrabarti S,Avasthi A,Sharma A,Sharma S

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:Studies from three independent laboratories report varying relationships between electrodermal hyporeactivity and suicidal behavior in depressed patients. The aims of this study were to explain that variation, to assess the discriminative validity of electrodermal hyporeactivity for suicide and suicide attemp...

journal_title：Acta psychiatrica Scandinavica

authors： Thorell LH

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:Prognostic studies of major depression have mainly focused on episode remission and relapse, and only a limited number of studies have examined long-term course of depressive symptomatology at threshold and subthreshold levels. METHOD:The Group for Longitudinal Affective Disorders Study has conducted prospec...

journal_title：Acta psychiatrica Scandinavica

authors： Furukawa TA,Yoshimura R,Harai H,Imaizumi T,Takeuchi H,Kitamura T,Takahashi K

更新日期：2009-04-01 00:00:00